This free case-based activity includes a crowd-sourced discussion of a 62-year-old woman with history of hypertension and monoclonal B-cell lymphocytosis (MBL) presents to your clinic with asymptomatic cervical, supraclavicular and inguinal lymphadenopathy. Her ECOG performance status is 0, and her LDH is elevated at 675 U/L (upper limit of normal 225). Excisional lymph node biopsy is performed. A preliminary pathology report gives a diagnosis of large B-cell lymphoma, pending FISH studies for final WHO subclassification.
1. Discuss the histopathologic criteria for high-grade B-cell lymphomas by the 2016 revised WHO Classification of Lymphoid Neoplasms
2. Describe first- and second-line therapies for diffuse large B-cell lymphomas and high-grade B-cell lymphomas in adults
3. Consider factors influencing utilization of chimeric antigen receptor (CAR) T-cell therapy in patients with aggressive B-cell lymphomas
Continuing Education Credit
1 Credit/Point is available for participation in this course. Certificate and credit types available include:
- AMA PRA Category 1 Credits™
- ABIM MOC Points
- CNE Contact Hours
- CPE Credits
- Certificate of Participation may be used to confer credit; however, all final decisions regarding the awarding of credits will be made by the licensing organization to which the credits are submitted.
- Certificate of Completion may be used to document participation, but no credit will be conferred.
Important Note: This course expires on February 20, 2021. Participants must complete all necessary course components by this date to receive credit.