This free case-based activity includes a crowd-sourced discussion of 2 cases: In Case #1, a 40-year old man developed a changing mole on his left upper back which revealed a 3.5 mm thick, ulcerated nodular melanoma with 8 mitoses per square millimeter. A lymph node disssection revealed 11 additional axillayr nodes, 2 of which were microscopically involved with melanoma. In case #2, a 45 year-old man who developed a right upper arm skin lesion, which revealted a 1.75 mm thick non-ulcerated superficial spreading melanoma with no evidence of ulceration and 1 mitosis per square millimeter, later then underwent a wide excision and sentinel lymph node evaluation, which showed no evidence of residual melanoma in the excision site and no evidence of involvement of either of the two identified right axillary sentinel lymph nodes. Originally posted on a forum in the ASCO Connection, users now have the opportunity to claim a CME, completion, or participation certificate for completing this activity.
- Evaluate treatment options for patients with selected melanoma diagnosis, considering targeted and immune therapy approaches in BRAF and NRAS mutations
- Determine the potential gene testing options available and explain why those selections are recommended and their prognostic significance.
- Discuss the therapeutic management of patients with melanoma using first-line and second-line therapy and in patients with CNS metastases.
This activity was made available on 10/30/2015 and will be reviewed on an annual basis to determine continued availability. A maximum of 1 AMA PRA Category 1 Credit(s) ™ credit is available.
Medical Knowledge (ACGME, AAPA) Health Promotion, Health Protection, Disease Prevention, and Treatment (ONS) Competencies Addressed Medical Knowledge (ACGME, AAPA) Health Promotion, Health Protection, Disease Prevention, and Treatment (ONS)