This free three-part activity highlights the acute need for trials involving adolescents and young adults, and provides practical information on how to find trials and on some of the factors regarding actual trial participation.
Part One: An Area of Urgent Need—This section will cover the need and relevance of including AYAs on clinical trials, especially as it relates to current care and outcomes.
- Examine the current level of adolescent and young adult (AYA) participation in clinical trials
- Discuss the benefits of and barriers to AYA participation in trials
- Recognize the importance of improving AYA clinical trial enrollment and support efforts to enhance participation
Part Two: What Are the Options?—This section will discuss options for clinical trials for AYAs, and will aim to raise awareness about including clinical trials as an option for therapy for these patients.
- Discuss key factors regarding trial access and treatment expertise, as they relate to the AYA patient population
- Describe distinguishing characteristics regarding trial goals and philosophy in adult versus pediatric oncology practice
- Identify measures and activities that are likely to lead to improved outcomes for AYA patients diagnosed with cancer and incorporate appropriate actions into practice
Part Three: Trial Participation—This section will cover the processes involved in trial participation, and will use a case scenario to depict issues arising during consent. It will also discuss the communications, time required, and shared care involved with these particular AYA patients.
- Review procedural steps involved in the consent, assent, re-consent and enrollment processes for clinical trials involving AYA patients
- Identify times when re-consenting is necessary for a subject of a clinical trial and apply this step when appropriate
- Define clinical equipoise and describe its application to the clinical trial enrollment process
- Clarify the care role of the primary oncologist versus that of the trial Principal Investigator
- Discuss unique issues that may be encountered by AYA patients during trial participation and develop strategies to address them. Issues to be considered may include treatment adherence, need for psychosocial support, and fertility preservation
CME credit is available for this course.
ACGME Competencies addressed: Medical Knowledge; Interpersonal and Communications Skills; Practice-based Learning & Improvement; Interpersonal & Communications Skills; Professionalism
This activity is co-sponsored by the LIVESTRONG Foundation, the Commission on Cancer/American College of Surgeons, Critical Mass: The Young Adult Cancer Alliance, the Association of Physician Assistants in Oncology, the American Society of Pediatric Hematology/Oncology, and the Conquer Cancer Foundation of the American Society of Clinical Oncology.
This initiative was supported by the Cooperative Agreement 5U50DP001689-05 from The Centers for Disease Control and Prevention. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the Centers for Disease Control and Prevention.
This course, as well as others in the Focus Under Forty Series, was also supported by the LIVESTRONG Foundation.