BRCA-Associated Breast Cancer

This is a case-based activity that includes discussion of a 39 year old G2P2 premenopausal woman presented with a new mass in her right breast.  Her family history is notable for paternal grandmother diagnosed at 42 with ovarian cancer; no family history of breast cancer.
Her gynecologist identified a 2 cm palpable mass in the upper outer quadrant, without axillary lymphadenopathy. 

A diagnostic mammogram and ultrasound revealed a 1.8 cm mass in the 2 o’clock position of the right breast. Image-guided core biopsy revealed poorly differentiated, invasive ductal carcinoma, estrogen receptor (ER) negative, progesterone receptor (PR) negative, and HER2 1+. HER2 negative by FISH (ratio 1.2). She is referred for multidisciplinary breast cancer management.  At the end of this course you should be able to:

  1. Describe the pathologic subtype of BRCA- associated breast cancer
  2. Discuss the surgical management of the breast and axilla in BRCA associated breast cancer
  3. Identify the optimal chemotherapy regimens for BRCA associated breast cancer

This activity was made available on 3/18/2015 and will be reviewed on an annual basis to determine continued availability. A maximum of 1 AMA PRA Category 1 Credit(s) ™ credit is available.

Competencies Addressed

Medical Knowledge (ACGME, AAPA)

Health Promotion, Health Protection, Disease Prevention, and Treatment (ONS)

Note: This course is now accessible through mobile devices as well as personal computers