2015 ASCO Journal Club: Hematologic Malignancies Fourth Quarter

Each quarter, ASCO’s experts review the leading journals, including the Journal of Clinical Oncology, to compile the most relevant, practice-changing science in hematologic malignancies. Reviews are presented in a didactic slide format, with audio commentary and links to references and resources and will focus on the following areas: translational science, clinical trials, reviews, guidelines, and editorials.

Articles covered in this quarter’s review include:

  • El-Galaly TC, Jakobsen LH, Hutchings M, et al. Routine Imaging for Diffuse Large B-Cell Lymphoma in First Complete Remission Does Not Improve Post-Treatment Survival: A Danish-Swedish Population-Based Study. J Clin Oncol. 2015 Dec 1;33(34):3993-8.
  • Leonard JP, Jung SH, Johnson J, et al. Randomized Trial of Lenalidomide Alone Versus Lenalidomide Plus Rituximab in Patients With Recurrent Follicular Lymphoma: CALGB 50401 (Alliance). J Clin Oncol. 2015 Nov 1;33(31):3635-40.
  • Scott DW, Mottok A, Ennishi D, et al. Prognostic Significance of Diffuse Large B-Cell Lymphoma Cell of Origin Determined by Digital Gene Expression in Formalin-Fixed Paraffin-Embedded Tissue Biopsies. J Clin Oncol. 2015 Sep 10;33(26):2848-56.

Learning Objectives

  • Examine the role of surveillance imaging in patient in first complete remission in diffuse large B-cell lymphoma
  • Explain that Lympho2x can be employed on formalin fixed paraffin embedded tissue to determine the cell of origin with incorporation of routine immunohistochemical stains to assess the prognosis in patients with diffuse large B-cell lymphoma
  • Recognize the role of rituximab and lenalidomide in the management of relapsed/refractory follicular lymphoma
  • Apply knowledge learned to enhance the care delivered to patients with hematologic malignancies

Continuing Education Credit

1 Credit/Point is available for participation in this course. Certificate and credit types available include:

  • AMA PRA Category 1 Credits™
  • Certificate of Participation may be used to confer credit; however, all final decisions regarding the awarding of credits will be made by the licensing organization to which the credits are submitted.
  • Certificate of Completion may be used to document participation, but no credit will be conferred. 

Important Notes

  • This course expires on December 16, 2018. Participants must complete all necessary course components by this date to receive credit.